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Warren MB, Stabler J, Hagman MM. 
“Intravenous melatonin abuse leading to recurrent aortic valve endocarditis: a case report and discussion”. 
BMC Psychiatry. 2016;16(1):39.
Reports of inappropriate medication use are widespread. There is a growing literature detailing abuse of drugs not typically thought to have high abuse liability. Melatonin is considered to be generally safe and is categorized by the Food and Drug Administration as a nutritional supplement. There are no known reports of intravenous melatonin abuse in the medical literature.
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