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Selegiline, bettern known as Deprenyl, is an MAO-B Inhibitor in small quantities (under 25 mg) and also inhibits MAO-A in larger quantities. It was the first selective inhibitor of MAO-B. Selegiline is marketed as a Parkinson's disease cure. Other reported positive effects include cognitive enhancement, increased libido in men, and reports of life-span extension.

Effects are described as stimulating and a little similar to cocaine. Tolerance builds relatively quickly. The FDA approved a Selegine transdermal patch (Emsam) for use as an antidepressant in February, 2006.
Dose #
5 -15 mg / day
Price #
Price Summary Needed.
Law #
Law Summary Needed.
Chemistry Summary Needed.
Pharmacology #
Pharmacology Summary Needed.
Production #
Production Summary Needed.
History #
Deprenyl was first developed in the early 1960s by Dr. Joseph Knoll.
Terminology / Slang #
Brand Names:
ldepryl; Carbex; Eprenyl; EJumex; Movergan; Plurimen; Alzene; Selpak; Atapryl.
The Substance:
l-Deprenyl; Selegiline.
The Experience:
No common terms known.
Effects Summary Needed.
Onset #
Onset Summary Needed.
Duration #
Duration Summary Needed.
Visual Effects #
Visuals Summary Needed.
Problems Summary Needed.
Contraindications #
  • Users of Emsam may be advised to avoid alcohol and foods containing tyramine.
  • Adverse effects are rare, but may include changes in blood pressure.
  • Pregnant women should consult their doctor before taking Deprenyl during pregnancy.

Addiction Potential #
Addiction Potential Summary Needed.
Long Term Health Problems #
Long Term Health Problems Summary Needed.
Risk of Death #
Risk of Death Summary Needed.
Erowid Basics pages are summaries of data gathered from site visitors, government documents, books, websites, and other resources. We do our best to keep this information correct and up-to-date, but the field is complex and constantly changing. Information should always be verified through multiple sources.