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Suzuki J, Dekker MA, Valenti ES, Arbelo Cruz FA, Correa AM, Poklis JL, Poklis A.
“Toxicities associated with NBOMe ingestion-a novel class of potent hallucinogens: a review of the literature”.
Psychosomatics. 2015 Mar-Apr 09;56(2):129-39.
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Abstract
BACKGROUND:
A new class of synthetic hallucinogens called NBOMe has emerged as drugs of abuse.
OBJECTIVE:
Our aim was to conduct a systematic review of published reports of toxicities associated with NBOMe ingestion.
METHODS:
We searched PubMed for relevant English-language citations that described adverse effects from analytically confirmed human NBOMe ingestion. Demographic and clinical data were extracted.
RESULTS:
A total of 10 citations met the criteria for inclusion, representing 20 individual patients. 25I-NBOMe was the most common analogue identified, followed by 25B-NBOMe and 25C-NBOMe. Fatalities were reported in 3 (15) cases. Of all the patients, 7 (35) were discharged after a period of observation, whereas 8 (40.0) required admission to an intensive care unit. The most common adverse effects were agitation (85.0), tachycardia (85.0), and hypertension (65.0). Seizures were reported in 8 (40.0) patients. The most common abnormalities reported on laboratory tests were elevated level of creatinine kinase (45.0), leukocytosis (25.0), and hyperglycemia (20.0).
CONCLUSIONS:
NBOMe ingestion is associated with severe adverse effects. Clinicians need to have a high index of suspicion for NBOMe ingestion in patients reporting the recent use of hallucinogens.
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