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Trial Run and Dosage Estimation
by Pfaffffed
From Bluelight Collection
Citation:   Pfaffffed. "Trial Run and Dosage Estimation: An Experience with 5-MeO-PiPT (exp115247)". Erowid.org. Jun 6, 2021. erowid.org/exp/115247

T+ 0:00
2 mg sublingual 5-MeO-PiPT
  T+ 0:35 2 mg sublingual 5-MeO-PiPT
  T+ 1:05 2 mg sublingual 5-MeO-PiPT
  T+ 1:45   inhaled Nitrous Oxide
  T+ 5:50 1 cup oral Tea



Initial impressions of 5-MeO-PiPT are that so far it seems to me like it's no more potent than 5-MeO-MiPT. It might be less potent, time will tell. I took 2mg, then after 35min took 2mg again, then again after twenty minutes. The time to onset and to full effects from each dose was remarkably fast on a completely empty stomach. I don't know if I ever made it past a strong + into a ++ or not. If I did, then the effects were mostly indistinguishable from 5-MeO-MiPT. I think when tolerance goes down, I'll try it again starting at 6mg all at once and adjust up from there. Because the overall dose was low and split up over a long period of time, I realistically don't think there's much that you can really take away from the rest of the report. You can stop reading now. ;-)

It was a little tenser and crampier than 5-MeO-MiPT, more along the lines of 4-HO-DiPT (and probably 5-MeO-DiPT, but I wouldn't know.) It didn't have the richness, empathy, appetite enhancement, or general satisfying feeling of life-experience enhancement of 5-MeO-MiPT. The somatic sensations might have been great at a higher dose. The libido enhancement wasn't there after the onset, and it generally felt a little dreamy and a little neutral. All of this is probably due to the low dose and the ROA, which was expected. I expect that it will have a lot more character at a higher dose, but given the complete lack of history of human use, I wanted to start low and slow. Frankly, I should have started lower and slower, and I just got lucky that the dosage of this drug was consistent with all of its close relatives. I enjoyed the onset and the peak, and I think I will enjoy this material even more at a proper dose. I doubt that it will end up being something that I'll have a place for given my affection for 5-MeO-MiPT, though. I will be interested to try vaping it at some point--maybe it will show more of its character that way.


I have experience with sixty or more different psychedelic compounds over the last few decades.


I slept for ten hours the night before, four hours of it were really restless and broken, with a constantly repeating dream about taking this drug. I'm guessing it was anxiety, since I couldn't find any information about people having taken it before. My sleep from 1am-7am was deep and restful, though, and I woke feeling fine but groggy. I had some ashwagandha, a strong matcha latte, and an iced coffee over the course of the next few hours. This eventually perked me up enough to go run some errands. I forgot to have breakfast due to the milky latte. Due to a half a glass of wine and 800mg kratom, I felt a little bit crappy by 10am and my bowels weren't happy with me. Neither alcohol nor kratom sit well with me any more.


10:10 I dissolve 10mg of the material sold as 5-MeO-PiPT in 1mL 95% ethanol. It dissolves readily. I measure out 2mL (2mg) and hold it under my tongue for least five seconds pass before I get some water to swallow. My stomach is still empty. I'm anticipating 40min to comeup, so I'll be waiting to see how this goes before re-dosing.

10:17 - 1st alert. Within minutes, the effects grow noticeably. This is unexpected. 5-MeO-MiPT usually comes on within 30min to just over an hour, averaging 40 minutes. I wonder if this has to do with the ROA, with the ethanol making it more available sublingually, so I got a faster onset. It doesn't seem likely.

10:30 - The effects are barely distinctive yet, with the sudden ramp up slowing down considerably, but still growing. It's mostly marked by some pleasant stimulation and a feeling of that 5-MeO-MiPT warmth and a hint of grit and muscle tightness. The crappy feeling that I had had from the tiny hangover from last night's amount of kratom and alcohol has been replaced with a good somatic feeling. There's a hint of tremoriness present, but it's faint. A brief and surprising bit of possibly placebo color shift manifested. I feel more vital, too, suggesting some erotic enhancement. I think I could be content at this dose, or even see microdosing this. I have a bit of chest tightness, but I've had that lately regardless.

10:45 - I'm take another 2mg at the +0:35min point. I can tell by my cold hands and feet that my blood sugar is low; I will need to figure out something to eat soonish. I'm getting a little shivery rush of euphoria up my spine and the front sides of my torso, as well as a little bit more muscle tightness. So far, I quite like this material, definitely more than 4-HO-PiPT.

10:51 - I feel the onset of the booster dose.

11:10 - I'm debating taking a final booster. It's far too early--I should wait another twenty minutes--but I'm getting quite hungry. Not a lot has happened since the last update. I'm at a pleasant +.

11:15 - I take another 2mg and go make a peanut butter and jelly sandwich. And some magnesium to head off muscle tension.

11:30 - Starting to come up on the third dose. I don't think I could tell this apart from 5-MeO-MiPT in a blind test at this stage. Maybe just through muscle tension. Appetite was unaffected--I ate a half a PB&J with a cup of a milk and a banana. It wasn't any better or worse than usual. The space is feeling more generic now, possibly due to the staggered dosing. If this is bi-phasic like 5-MeO-MiPT, I hope that this staggering doesn't lock me in to the first stage for the whole experience as people report with 5-MeO-MiPT.

11:40 - The headspace is stronger headspace now, but it's still pretty clear. The somatic feelings are really subtle, but I think they would be quite pleasurable at a higher dosage. There's zero visual activity to speak of.

11:55 - I just used some nitrous. I became aware of how much less pleasurable it has been lately compared to how it was years ago. The same is true for alcohol. This made me think that as people have said all through history, youth is wasted on the young. The pleasures of life exist in a gradient, and wick away as we age, leaving less there for us to enjoy as that space is occupied by an increasingly burdensome aches and pains of a slowly failing body. Bleak as this is, it's also an affirmation to throw myself fully into enjoying the moment, because postponing present happiness for a payoff in the future by this logic seems doomed. I'm aware that these thoughts are nitrous inflected, and that I may discard them as invalid when the effects wear off.

1:00 - I'm solidly in the plateau now I must conclude, as I've been thinking for some time. What a shame--I don't think this is going to progress anywhere interesting. I knew that was what I had hoped for setting out today, aiming to underdose but get a feel for what a proper active dose may be, but it's still a bummer. I got to a strong + or maybe a ++ during this experience, and it was quite pleasant. It seemed more clearheaded than 5-MeO-MiPT. It lacked the visuals, the enhancement, the empathy, the hunger. The nondescript character is likely a product of the low, staggered dose. I think next time I will start at 6mg all at once, then titrate up. I have 4mg still sitting out, but I'm sure that all it would do now is extend the duration. Far from being an annoying hanger-on space, this place seems nice enough. I just have to come to terms with the fact that the rest of the experience is probably not going anywhere interesting.

It turned out that sex was not enhanced in terms of somatic sensations or emotional qualities. My desire was not any higher than normal during the plateau, maybe even a tiny bit lower, but I had not trouble getting or maintaining an erection. The neutral libido contrasted with how I was feeling earlier in the experience. I was at least more mentally present during sex, which made it more satisfying than when sober. Orgasm felt normal. All this again is likely due to dose and due to the fact that I'm already mid-plateau.

1:40 - My friend and I just got back from a half an hour walk. It was a beautiful day outside, which was nice. There was nothing really of note that happened. I would have enjoyed it more if my guts hadn't been a little gas-crampy.

2:00 - I have a little bit of a libido again as this very slowly wears off.

2:26 - After finally farting, my gas cramps subsided. I had a second orgasm, and am now noticing that I'm a little hungry. The effects seem to be waning even more now.

3:00 - Made some salad and a frozen pizza, which was manageable both to eat and prepare. Noteworthy in that it wasn't noteworthy--eating is usually a chore for me on most non-MiPT family psychedelics.

4:00 - Still not entirely at baseline. I've been yawning a fair bit for an hour. Some 4C-D sounds nice, but who the hell know what drug interactions there are with this one. I don't anticipate any, but 5-MeO-DMT and 5-MeO-aMT both interact weirdly, so I'm playing it safe. I would normally avoid mixing to see what the true duration of the material is, but I think I hosed that with the staggered dosing anyway. I think I'll just make some green tea.

5:00 - The headspace is still remarkably stable. I'm still far from down. The farting at least has stopped. This is about seven hours from when I initially dosed, and I'm sober enough to start working on chores around the house, but not sober enough to want to. I hope that future experiences have a little more richness and character to their plateaus. I expect they will. If not, I could see vaping this instead of taking it orally to maximize the positives and reduce the duration.

Exp Year: 2021ExpID: 115247
Gender: Not Specified 
Age at time of experience: 38 
Published: Jun 6, 2021Views: 1,598
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5-MeO-PIPT (946) : Unknown Context (20), First Times (2)

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