In book IIII.75: "The root has a property that causes not unpleasant fantasies when a quantity of one drachma is drunk with wine, but when a quantity of two drachmai is drunk, it drives a person out of his senses for up to three days; and if a quantity of four drachmai is drunk, it kills; drinking and vomiting large quantities of hydromel is its antidote."

For example, the Tantra states "[M]aking an image of the enemy with the excrement and urine of those who follow the great Dharma, wrathfully burn it in a fire of thorn-wood, and even the Buddha will certainly perish. [...] So he said black mustard-seeds, salt, oil, poison, and thorn-apple [datura], these are taught as the supreme destroyers of all the Buddhas."

Robert Beverly wrote of the incident in 1705:

"The James-Town Weed (which resembles the Thorny Apple of Peru, and I take to be the Plant so call'd) is supposed to be one of the greatest Coolers in the World. This being an early Plant, was gather'd very young for a boil'd Salad, by some of the Soldiers sent thither, to pacific the Troubles of Bacon; and some of them eat plentifully of it, the Effect of which was a very pleasant Comedy; for they turn'd natural Fools upon it for several Days: One would blow up a Feather in the Air; another wou'd dart Straws at it with much Fury; and another stark naked was sitting up in a Corner, like a Monkey, grinning and making Mows at them; a Fourth would fondly kiss, and paw his Companions, and snear in their Faces, with a Countenance more antick, than any in a Dutch Droll. In this frantick Condition they were confined, lest they should in their Folly destroy themselves; though it was observed, that all their Actions were full of Innocence and good Nature. Indeed, they were not very cleanly; for they would have wallow'd in their own Excrements, if they had not been prevented. A Thousand such simple Tricks they play'd, and after Eleven Days, return'd to themselves again, not remembring any thing that had pass'd."

In the TV western series The Rifleman, a man is killed when an Apache witch doctor poisons his coffee with jimson weed (Datura spp.). The man hallucinates, has a high fever, has a paranoid reaction, and dies a few hours later.

The doctor says 'jimson weed can cause a man to have visions and fits too'. The main character, Lucas McCain asks, 'Is that what the indians call the trumpet flower?'. Later in the episode McCain picks a spray of flowers from a plant and snarls jimson weed, despite the plant looking nothing like any Datura species.

Federal Register entry attached to Microgram issue referenced.

Held in Madison, Wisconsin.