Chemicals marked on Erowid by our Research Chemical Symbol should be considered experimental chemicals. Although some people are willing to ingest these chemicals for their effects, it is not reasonable to assume that these chemicals are in any way 'safe' to use recreationally. Although all psychoactive use involves risk, many substances in this class of chemicals have undergone virtually no human or animal toxicity studies. Research chemicals are those for which there is little to no data on possible long term problems, addiction potential, allergic reactions, or acute overdoses.

Publication of information by Erowid about human use of these chemicals is not intended to endorse their non-laboratory use. It is important to remember that reactions to psychoactives vary dramatically from person to person. Extrapolating anything from any single person's experience with a chemical is inappropriate and may result in dangerous and possibly fatal adverse reactions.

Some reports of use may include extremely glowing "wow"-type experiences. Reports of this nature should not be misunderstood to suggest that they are common or typical of those who ingest the substance, or that the effects will be pleasant or desirable.

Additionally, the reliability of many sources of these products can be questionable. Mislabeling, misidentification, issues of purity, adulteration, and misrepresentation (substitution) are unfortunately a common problem with research chemicals.

Consider carefully before choosing to use these substances.