Erowid References Database
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Cameron OG, Appel JB.
“Drug Induced Conditioned Suppression: Specificity Cue To Drug Employed As Ucs”.
Pharmacol. Biochem. Behav.. 1976;4(2):221-224.
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Abstract
THE CLASSICAL CONDITIONING POTENTIAL OF SEVERAL DRUGS HAS TESTED IN RATS BY PAIRING A LIGHT-CS WITH THE DRUG UCSS; THESE STIMUII WERE SUPERIMPOSED ON A VARIABLE INTERVAL 30 SEC SCHEDULE FOR WATER REINFORCEMENT. CONDITIONING (SUPPRESSION OF BAR PRESSING IN THE PRESENCE OF THE CS) HAS DEFINITELY DEMONSTRATED WITH PSILOCYBIN (2.0 MG/KG). WAS SUGGESTED BUT NOT CLEARLY SHOWN WITH LSD (0.13 MG/KG), AND WAS NOT EVIDENT WITH METHYL ATROPINE NITRATE (50 MG/KG) OR PENTOBARBITAL (25 MG/KG). THESE RESULTS INDICATE THAT PREVIOUSLY DEMONSTRATED DRUG INDUCED CONDITIONED SUPPRESSION IS NOT A NONSPECIFIC EFFECT OF UNCONDITIONED SUPPRESSION BUT DEPENDS ON THE TYPE OF DRUG EMPLOYED.
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