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Kräuchi K, Lichtsteiner M, Feer H, Wirz-Justice A. 
“Demonstration of an in vivo d-LSD-binding method”. 
Experientia. 1978;34(7):926.
A reproducible in vivo d-LSD binding method in rat brain has been developed, with high affinity (Kd of 5 pmoles/g ww), stereospecificity (d- vs l-LSD) and regional Selectivity. It may be a useful adjunct to in vitro methods for measuring changes in turnover at the synaptic level related to the intact receptor. Application of this method to differentiation of serotoninergic and dopaminergic components of the LSDbinding Site by different agonist/antagonist drugs was attempted.
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