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Nadel E, Burstein S, Hoagland H. 
“Comparative effects of ACTH and LSD on urinary corticosteroids in guinea pigs”. 
Amer. J. Physiol.. 1957;189:73.
Effects of lysergic acid diethylamide (LSD) and of adrenocorticotrophic hormone (ACTH), administered alone and in combination, on the urinary excretion of three corticosteroids, 6ß hydroxycortisol, 2agr hydroxycortisol and cortisol, were compared in four series (11 g.p./series) using inbred strain 2 guinea pigs to see whether some of the effects of LSD were mediated by way of pituitary gland stimulation. ACTH (10 mg) significantly increased the urinary excretion values of the three corticosteroids. There was no increase in corticosteroids following administration of LSD (50 mg). LSD given in combination with ACTH at the above doses did not alter the values observed after ACTH alone.
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