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Lopes NP, Chicaro P, Kato MJ, Albuquerque S, Yoshida M. 
“Flavonoids and lignans from Virola surinamensis twigs and their in vitro activity against Trypanosoma cruzi”. 
Planta Med. 1998 Oct 16;64(7):667-8.
Dichloromethane extracts from twigs of Virola surinamensis (Myristicaceae) showed in vitro trypanosomicidal activity against trypomastigote form of Trypanosoma cruzi. The extract, fractionated by preparative circular chromatography and preparative high-performance liquid chromatography yielded two steroids, two lignans, five flavonoids, and one polyketide. Among the isolated compounds, the lignans presented the highest trypanosomicidal activity.
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