We are currently investigating the pharmacological properties of 2-aminotetralins and related compounds using biochemical and behavioral methods recently published.
It has been previously shown that 5-hydroxy-(l), 6-hydroxy- (2) and 'I-hydroxy-2-(di-n-propylamino)-tetralin (3) exhibit considerable dopamine (DA) receptor stimulating activity.31~I n this series, the 5-hydroxy isomer 1 is the most active compound, being a highly active central DA-receptor agonist.
