The NBOMe series of chemicals are primarily N-o-methoxybenzyl analogs of the 2C-X family of phenethylamines, and are 5-HT2A (serotonin 2A) receptor agonists. A few are amphetamine analogs. With few exceptions (e.g. mescaline-NBOMe), compounds in this group are active at very low (sub-milligram) doses. These chemicals have nearly no history of human use prior to 2010 when they first became available online.